ANU Home | HORUS | Staff Home | Students | RSBS

Dr Nicolas Goffard

Current Research

Microarray technologies provide a comprehensive overview of mechanisms involved in the cell by revealing the expression of thousands of genes simultaneously. I am involved in a bioinformatics project to develop methods for the analysis of gene expression on legumes, using data from transcriptomics, proteomics and metabolomics experiments. Current work includes annotation and classification of legumes such as soybean or Medicago truncatula transcripts present, in the Affymetrix Genome Arrays in order to analyse and visualize their gene expression in a functional context.

Academic Qualifications

PhD University of Bordeaux, France (Bioinformatics; 2004)
MSc University of Bordeaux, France (Computational Biology; 2001)
MSc University of Bordeaux, France (Oenology/Molecular Biology; 2000)
BSc University of Bordeaux, France (Cellular Biology/Physiology/Microbiology; 1999)

Relevant Employment History

2005-present Australian National University Canberra, Postdoctoral Fellow
2005 Assistant Lecturer and Researcher in Bordeaux Bioinformatics Center and in Department of Computer Science and Mathematics, University of Bordeaux, France

Recent Publications

Goffard N. and Weiller G. (2007) "PathExpress: a web-based tool to identify relevant pathways in gene expression data." Nucleic Acids Res., in press.

Goffard N. and Weiller G. (2007) "Identifying components of complexes." Bioinformatics Methods in Molecular Biology Series, Human Press, in press.

van Noorden G., Kerim T., Goffard N., Wiblin R., Pellerone F., Rolfe B., Mathesius U. (2007) "Overlap proteome changes in Medicago truncatula in response to Auxin and Sinorhizobium meliloti." Plant Physiology, pp.107.0099978.

Goffard N. and Weiller G. (2007) "GeneBins: a database for classifying gene expression, with application to plant genome arrays". BMC Bioinformatics, 8:87.

Goffard N. and Weiller G. (2006) "Extending MapMan: Application to legume genome arrays." Bioinformatics, 22(23): 2958-2959.

Barriot R., Poix J., Groppi A., Barre A., Goffard N., Sherman D., Dutour I., de Daruvar A. (2004) "A new strategy for the representation and the integration of biomolecular knowledge at a cellular scale." Nucleic Acids Res., 32: 3581-3589.

Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., De Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., De Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hatraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.L. (2004) "Genome evolution in yeasts." Nature, 430: 35-44.

Iragne F., Barre A., Goffard N., De Daruvar A. (2004) "AliasServer: a web server to handle multiple aliases used to refer to proteins." Bioinformatics, 20: 2331-2332.

Goffard N., Garcia V., Iragne F., Groppi A., de Daruvar A. (2003) "IPPRED: server for proteins interactions inference." Bioinformatics, 19: 903-904.